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Planning radiation fields would require a visible margin of a melanoma in situ or documented mapping biopsies showing the margin of the lesion

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Yang T, Richards EM, Pepine CJ, et al

ODC (ornithine decarboxylase)-dependent putrescine synthesis maintains MerTK (MER tyrosine-protein kinase) expression to drive resolution

However, some users find that the dual-action approach creates a more systemic feeling during the first few weeks, which may include the body aches in question

Most providers recommend continuing at a stable maintenance dose unless you and your clinician decide discontinuation fits your goals